Student: Leyla Selman, senior
Mentor: Dr. Benjamin Hopkins, Icahn School of Medicine, Mount Sinai
Leyla Selman always has been interested in science and solving problems. For her Science Research Program project, she was inspired by her mother, who battled cancer, to research testing potential treatment drugs for ovarian cancer tumors.
“My project focused on a gene mutation in ovarian cancer tumors and explored potential treatment options for ovarian cancer patients,” said Selman.
The project involved a significant amount of statistical analysis, given the sheer amount of data she had to review. What she ultimately found was that Taselisib, a cancer drug, would not be an effective treatment in cancer patients who have a mutation in the PTEN gene, which regulates the creation of an important enzyme found in almost all of the body’s tissues.
Taselisib is still an experimental drug, meaning there is plenty of research yet to be done on its capabilities for treatment. Selman’s research already has found one likely limitation of its application in its inability to treat cancer patients with the PTEN mutation. It remains to be seen what further studies will reveal regarding its effectiveness.
Selman hopes her experience in the Science Research Program is only the beginning of her scientific journey.
“I want to get involved with science research in college, and this program has helped me build a strong foundation of knowledge in my area of interest that will be very helpful in my future research endeavors,” she said. “Additionally, the presentation aspect of science research has really helped me build confidence in my speaking and presenting skills.”
Moreover, the program has helped her find greater joy in the field of science research as she has progressed in her work alongside friends and fellow students.
“I think the most rewarding part of being in [the program] is being able to bond with my peers over our shared interest in science, and I’ve been able to make some great friends throughout my four years in the program,” she said.